| Item Type | Name |
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Concept
|
Antigen-Presenting Cells
|
|
Concept
|
Adenosine Triphosphatases
|
|
Concept
|
Adenosine Triphosphate
|
|
Concept
|
Cell Communication
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|
Concept
|
Antigens, Differentiation, T-Lymphocyte
|
|
Concept
|
Cell Differentiation
|
|
Concept
|
Cell Movement
|
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Concept
|
Cell Nucleus
|
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Concept
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Biological Transport
|
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Concept
|
Cell Membrane
|
|
Concept
|
Cell Separation
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Concept
|
Clone Cells
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Concept
|
Cell Transformation, Neoplastic
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Concept
|
Diabetes Mellitus, Type 1
|
|
Concept
|
Dendritic Cells
|
|
Concept
|
Cytotoxicity Tests, Immunologic
|
|
Concept
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Epithelial Cells
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|
Concept
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Killer Cells, Natural
|
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Concept
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Genetic Complementation Test
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|
Concept
|
Hematopoietic Stem Cells
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Concept
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Immune Tolerance
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Concept
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Histocompatibility Testing
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Concept
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Mice, Transgenic
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Concept
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Organ Culture Techniques
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Concept
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HeLa Cells
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Concept
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Plasma Cells
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Concept
|
Protein-Tyrosine Kinases
|
|
Concept
|
Protein Processing, Post-Translational
|
|
Concept
|
Immunoenzyme Techniques
|
|
Concept
|
Salmonella typhimurium
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Concept
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Taurine
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|
Concept
|
Time Factors
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|
Concept
|
Transcription, Genetic
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Concept
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Tretinoin
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Concept
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Interferon Type I
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Concept
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Transformation, Bacterial
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|
Concept
|
Th1 Cells
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|
Concept
|
Gene Rearrangement, T-Lymphocyte
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
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|
Concept
|
Transforming Growth Factor beta
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|
Concept
|
Receptors, Antigen, T-Cell, gamma-delta
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Concept
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CD4-Positive T-Lymphocytes
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Concept
|
Lymphocytes, Tumor-Infiltrating
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|
Concept
|
Tacrolimus
|
|
Concept
|
Liver Transplantation
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Concept
|
T-Lymphocyte Subsets
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|
Concept
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T-Cell Antigen Receptor Specificity
|
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Concept
|
Protein Structure, Tertiary
|
|
Concept
|
Receptors, Antigen, T-Cell, alpha-beta
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|
Concept
|
Treatment Outcome
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|
Concept
|
Self Tolerance
|
|
Concept
|
CD8-Positive T-Lymphocytes
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Genes, T-Cell Receptor
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|
Concept
|
Epitopes, T-Lymphocyte
|
|
Concept
|
Jurkat Cells
|
|
Concept
|
Primary Cell Culture
|
|
Concept
|
STAT Transcription Factors
|
|
Concept
|
Toll-Like Receptor 1
|
|
Concept
|
Toll-Like Receptor 6
|
|
Concept
|
Caco-2 Cells
|
|
Concept
|
Goblet Cells
|
|
Concept
|
Organic Cation Transport Proteins
|
|
Concept
|
Transglutaminases
|
|
Concept
|
Transforming Growth Factor beta1
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|
Concept
|
Tissue Distribution
|
|
Concept
|
HEK293 Cells
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|
Concept
|
Molecular Targeted Therapy
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|
Concept
|
GATA4 Transcription Factor
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|
Concept
|
High-Throughput Nucleotide Sequencing
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Insulin-Secreting Cells
|
|
Concept
|
T-Lymphocytes, Cytotoxic
|
|
Concept
|
Taurocholic Acid
|
|
Concept
|
Triticum
|
|
Concept
|
NFATC Transcription Factors
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|
Concept
|
NK Cell Lectin-Like Receptor Subfamily K
|
|
Concept
|
Toll-Like Receptor 2
|
|
Concept
|
Toll-Like Receptor 4
|
|
Concept
|
Transfection
|
|
Concept
|
Treatment Failure
|
|
Concept
|
Lymphoma, T-Cell
|
|
Concept
|
Stromal Cells
|
|
Concept
|
Receptors, Natural Killer Cell
|
|
Concept
|
NK Cell Lectin-Like Receptor Subfamily C
|
|
Concept
|
Gene Targeting
|
|
Concept
|
Cell Lineage
|
|
Concept
|
Paneth Cells
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|
Concept
|
T-Lymphocytes, Regulatory
|
|
Concept
|
Toll-Like Receptor 7
|
|
Concept
|
Transcriptome
|
|
Concept
|
Tumor Microenvironment
|
|
Concept
|
Lectins, C-Type
|
|
Concept
|
Programmed Cell Death 1 Receptor
|
|
Concept
|
Cell Line, Tumor
|
|
Concept
|
ZAP-70 Protein-Tyrosine Kinase
|
|
Concept
|
Forkhead Transcription Factors
|
|
Concept
|
Intention to Treat Analysis
|
|
Concept
|
Th17 Cells
|
|
Concept
|
Cell Line
|
|
Concept
|
Cell Survival
|
|
Concept
|
Cells, Cultured
|
|
Concept
|
Clinical Trials as Topic
|
|
Concept
|
Receptors, Antigen, T-Cell
|
|
Concept
|
T-Lymphocytes
|
|
Concept
|
Thymus Gland
|
|
Concept
|
Transplantation, Homologous
|
|
Concept
|
Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor
|
|
Concept
|
Signal Transduction
|
|
Concept
|
Cell Degranulation
|
|
Concept
|
Coculture Techniques
|
|
Concept
|
Gastrointestinal Tract
|
|
Concept
|
Microscopy, Electron, Transmission
|
|
Concept
|
NK Cell Lectin-Like Receptor Subfamily D
|
|
Academic Article
|
Abnormal intestinal intraepithelial lymphocytes in refractory sprue.
|
|
Academic Article
|
Distinction between coeliac disease and refractory sprue: a simple immunohistochemical method.
|
|
Academic Article
|
Selective expansion of intraepithelial lymphocytes expressing the HLA-E-specific natural killer receptor CD94 in celiac disease.
|
|
Academic Article
|
NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment.
|
|
Academic Article
|
TCR specificity dictates CD94/NKG2A expression by human CTL.
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|
Academic Article
|
Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease.
|
|
Academic Article
|
Is celiac disease an autoimmune disorder?
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|
Academic Article
|
Human CD8+ intraepithelial lymphocytes: a unique model to study the regulation of effector cytotoxic T lymphocytes in tissue.
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|
Academic Article
|
Plague bacteria target immune cells during infection.
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Academic Article
|
Mechanisms of disease: immunopathogenesis of celiac disease.
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|
Academic Article
|
Expression of nonclassical class I molecules by intestinal epithelial cells.
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|
Academic Article
|
The Bacillus subtilis quorum-sensing molecule CSF contributes to intestinal homeostasis via OCTN2, a host cell membrane transporter.
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|
Academic Article
|
Small intestinal CD8+TCRgammadelta+NKG2A+ intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease.
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|
Academic Article
|
LcrV plague vaccine with altered immunomodulatory properties.
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|
Academic Article
|
Cytosolic PLA2 is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15.
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|
Academic Article
|
The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity.
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Academic Article
|
Regional mucosa-associated microbiota determine physiological expression of TLR2 and TLR4 in murine colon.
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|
Academic Article
|
NKG2D initiates caspase-mediated CD3zeta degradation and lymphocyte receptor impairments associated with human cancer and autoimmune disease.
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|
Academic Article
|
Gliadin regulates the NK-dendritic cell cross-talk by HLA-E surface stabilization.
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|
Academic Article
|
Massive interleukin-12-induced interferon-gamma production by interleukin-15-stimulated lamina propria lymphocytes followed by down-regulation of the interleukin-12 receptor.
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|
Academic Article
|
The role of HLA-DQ8 beta57 polymorphism in the anti-gluten T-cell response in coeliac disease.
|
|
Academic Article
|
Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens.
|
|
Academic Article
|
Coeliac disease and gluten sensitivity.
|
|
Academic Article
|
Densely granulated murine NK cells eradicate large solid tumors.
|
|
Academic Article
|
The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota.
|
|
Academic Article
|
Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice.
|
|
Academic Article
|
Extracellular transglutaminase 2 is catalytically inactive, but is transiently activated upon tissue injury.
|
|
Academic Article
|
Celiac disease and transglutaminase 2: a model for posttranslational modification of antigens and HLA association in the pathogenesis of autoimmune disorders.
|
|
Academic Article
|
NKG2 receptor-mediated regulation of effector CTL functions in the human tissue microenvironment.
|
|
Academic Article
|
Reprogramming of CTLs into natural killer-like cells in celiac disease.
|
|
Academic Article
|
Regional differences in colonic mucosa-associated microbiota determine the physiological expression of host heat shock proteins.
|
|
Academic Article
|
Potential celiac patients: a model of celiac disease pathogenesis.
|
|
Academic Article
|
Pathophysiology of celiac disease.
|
|
Academic Article
|
Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis.
|
|
Academic Article
|
Tissue-mediated control of immunopathology in coeliac disease.
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|
Academic Article
|
Selection and expansion of CD8alpha/alpha(1) T cell receptor alpha/beta(1) intestinal intraepithelial lymphocytes in the absence of both classical major histocompatibility complex class I and nonclassical CD1 molecules.
|
|
Academic Article
|
Refractory sprue, coeliac disease, and enteropathy-associated T-cell lymphoma. French Coeliac Disease Study Group.
|
|
Academic Article
|
Don't move: LRRK2 arrests NFAT in the cytoplasm.
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|
Academic Article
|
A specific role for TLR1 in protective T(H)17 immunity during mucosal infection.
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|
Academic Article
|
The majority of CD1d-sulfatide-specific T cells in human blood use a semiinvariant Vd1 TCR.
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|
Academic Article
|
Small bowel transplantation alone or with the liver in children: changes by using FK506.
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|
Academic Article
|
syk protein tyrosine kinase regulates Fc receptor gamma-chain-mediated transport to lysosomes.
|
|
Academic Article
|
IL-15 in tumor microenvironment causes rejection of large established tumors by T cells in a noncognate T cell receptor-dependent manner.
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|
Academic Article
|
Triggers and drivers of autoimmunity: lessons from coeliac disease.
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|
Academic Article
|
Crystal structure of Vd1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human ?d T cells.
|
|
Academic Article
|
Human NKG2E is expressed and forms an intracytoplasmic complex with CD94 and DAP12.
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|
Academic Article
|
How T cells taste gluten in celiac disease.
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|
Academic Article
|
Interleukin 15 primes natural killer cells to kill via NKG2D and cPLA2 and this pathway is active in psoriatic arthritis.
|
|
Academic Article
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Insulin-dependent diabetes induced by pancreatic beta cell expression of IL-15 and IL-15Ra.
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Academic Article
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Elevated T cell receptor signaling identifies a thymic precursor to the TCRaß(+)CD4(-)CD8ß(-) intraepithelial lymphocyte lineage.
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Academic Article
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IL-15: a central regulator of celiac disease immunopathology.
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Academic Article
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Innate immunity: actuating the gears of celiac disease pathogenesis.
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Academic Article
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Distinct and Synergistic Contributions of Epithelial Stress and Adaptive Immunity to Functions of Intraepithelial Killer Cells and Active Celiac Disease.
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|
Academic Article
|
Cysteinyl leukotrienes mediate lymphokine killer activity induced by NKG2D and IL-15 in cytotoxic T cells during celiac disease.
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Academic Article
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Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A.
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Academic Article
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Intestinal microbiota modulates gluten-induced immunopathology in humanized mice.
|
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Academic Article
|
IMMUNOLOGY. Breaching the gut-vascular barrier.
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Academic Article
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IL-15 functions as a danger signal to regulate tissue-resident T cells and tissue destruction.
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Academic Article
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Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy.
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Academic Article
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The features of mucosa-associated microbiota in primary sclerosing cholangitis.
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Academic Article
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A dendritic cell subset designed for oral tolerance.
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Academic Article
|
Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development.
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Academic Article
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Interleukin-15 promotes intestinal dysbiosis with butyrate deficiency associated with increased susceptibility to colitis.
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Academic Article
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Early Transcriptomic Changes in the Ileal Pouch Provide Insight into the Molecular Pathogenesis of Pouchitis and Ulcerative Colitis.
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Academic Article
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Early Transcriptomic Changes in the Ileal Pouch Provide Insight into the Molecular Pathogenesis of Pouchitis and Ulcerative Colitis.
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Academic Article
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Open-Capsule Budesonide for Refractory Celiac Disease.
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|
Academic Article
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T Cells in Celiac Disease.
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|
Academic Article
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Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease.
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|
Academic Article
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Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies.
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Academic Article
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Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors.
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Academic Article
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Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.
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Academic Article
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Single-Cell RNA Sequencing of Blood and Ileal T Cells From Patients With Crohn's Disease Reveals Tissue-Specific Characteristics and Drug Targets.
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Academic Article
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Natural polyreactive IgA antibodies coat the intestinal microbiota.
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Academic Article
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Dietary antioxidant micronutrients alter mucosal inflammatory risk in a murine model of genetic and microbial susceptibility.
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Academic Article
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Murine Norovirus Infection Induces TH1 Inflammatory Responses to Dietary Antigens.
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Academic Article
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Reovirus-Induced Apoptosis in the Intestine Limits Establishment of Enteric Infection.
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Academic Article
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A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease.
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Academic Article
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Epithelial IL-15 Is a Critical Regulator of ?d Intraepithelial Lymphocyte Motility within the Intestinal Mucosa.
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Academic Article
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A viral trigger for celiac disease.
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Academic Article
|
Human intraepithelial lymphocytes.
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Academic Article
|
P31-43, an undigested gliadin peptide, mimics and enhances the innate immune response to viruses and interferes with endocytic trafficking: a role in celiac disease.
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|
Academic Article
|
Diverse developmental pathways of intestinal intraepithelial lymphocytes.
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Academic Article
|
Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1?E9 murine model of Alzheimer's disease.
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Academic Article
|
Mitochondria maintain controlled activation state of epithelial-resident T lymphocytes.
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Academic Article
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Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease.
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|
Academic Article
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Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2.
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|
Academic Article
|
Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease.
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|
Academic Article
|
Identification of a ?c Receptor Antagonist That Prevents Reprogramming of Human Tissue-resident Cytotoxic T Cells by IL15 and IL21.
|
|
Academic Article
|
Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes.
|
|
Academic Article
|
IL-15, gluten and HLA-DQ8 drive tissue destruction in coeliac disease.
|
|
Academic Article
|
Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity.
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|
Academic Article
|
High-sensitivity C-reactive protein is associated with clonal hematopoiesis of indeterminate potential.
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Academic Article
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Transglutaminase 2 Inhibition for Prevention of Mucosal Damage in Celiac Disease.
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Academic Article
|
A multilayered immune system through the lens of unconventional T cells.
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Academic Article
|
High molecular weight DNA extraction strategies for long-read sequencing of complex metagenomes.
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|
Academic Article
|
An efficient urine peptidomics workflow identifies chemically defined dietary gluten peptides from patients with celiac disease.
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|
Academic Article
|
Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis.
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|
Academic Article
|
Innate riddle of CD4+ T cells and the control of enteric infections.
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|
Academic Article
|
A Mouse Model of Celiac Disease.
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Academic Article
|
Paired bone marrow and peripheral blood samples demonstrate lack of widespread dissemination of some CH clones.
|
|
Academic Article
|
LRP-1 links post-translational modifications to efficient presentation of celiac disease-specific T cell antigens.
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|
Academic Article
|
Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection.
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|
Academic Article
|
NK cells contribute to reovirus-induced IFN responses and loss of tolerance to dietary antigen.
|
|
Academic Article
|
GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology.
|
|
Concept
|
Fecal Microbiota Transplantation
|
|
Concept
|
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
|
|
Concept
|
In Vitro Techniques
|
|
Grant
|
Regulation of normal human IEL by NKG2D and IL-15
|
|
Grant
|
Innate and adaptive immunity in celiac disease
|
|
Grant
|
Center for Interdisciplinary Study of Inflammatory Intestinal DIsorders (C-IID)
|
|
Grant
|
GATA4 as a window into the link between metabolism and immunity
|
|
Grant
|
Localizing Pathogenically Relevant Transglutaminase 2 in Celiac Disease
|
|
Grant
|
Role of Transglutaminase 2 in Celiac Sprue
|
|
Academic Article
|
Metabolic independence drives gut microbial colonization and resilience in health and disease.
|
|
Academic Article
|
The gut protist Tritrichomonas arnold restrains virus-mediated loss of oral tolerance by modulating dietary antigen-presenting dendritic cells.
|
|
Academic Article
|
Inflammation in the proximal colon is a risk factor for the development of colorectal neoplasia in inflammatory bowel disease patients with primary sclerosing cholangitis.
|
|
Academic Article
|
Microbial-enrichment method enables high-throughput metagenomic characterization from host-rich samples.
|
|
Academic Article
|
Epithelial IFN? signalling and compartmentalized antigen presentation orchestrate gut immunity.
|
|
Academic Article
|
Restoring tolerance with antigen delivery.
|
|
Academic Article
|
Pseudo-spectral angle mapping for automated pixel-level analysis of highly multiplexed tissue image data.
|